From the Literature

 

Published: Nov 2014

Albumin administration is associated with acute kidney injury in cardiac surgery: a propensity score analysis.
Frenette A, Bouchard J, Bernier P, et al.
Crit Care 2014;18:602.
Pub Med
NATA rating :

 

REVIEW by:
P. Van der Linden

 

NATA REVIEW:
In this retrospective study including 984 patients undergoing cardiac surgery, the authors observed that perioperative albumin administration was associated with an increased risk of acute kidney injury. This effect was proportional to the dose administered and remained significant even in patients without postoperative haemodynamic instability.

This observation should be confirmed in further prospective randomised control trials. Of note, the use of HES 130/0.4 in this particular population was not associated with an increased risk of acute kidney injury.

- Philippe Van der Linden