From the Literature

 

Published: Nov -0001

Successful use of recombinant factor VIIa for massive bleeding after Caesarean section due to HELLP syndrome.

Salek SZ, Sokolic V, Viskovic T, Sanjug J, Simic M, Kastelan M

Acta Haematol 2002;108(3):162-163.

Pub Med
NATA rating :

 

REVIEW by:
Aldouri M

 

NATA REVIEW:
This is a case report on a 31-yr-old woman who suffered with severe post-partum hemorrhage (PPH) following a cesarean section because of severe HELLP syndrome. She did not respond to massive transfusion of blood components, and had laboratory evidence of severe DIC. She eventually had a remarkable response to one dose of rFVIIa at a dose of 90 μg/kg and did not require further transfusions. There was a similar case report of PPH and DIC following cesarean section which responded to rFVIIa (Moscardo F et al, Br J Haematol 2001; 113:174-6).


- Maadh Aldouri