From the Literature

Published: Oct 2014

Welsh KJ, Padilla A, Dasgupta A, Nguyen AN, Wahed A

Thromboelastography is a suboptimal test for determination of the underlying cause of bleeding associated with cardiopulmonary bypass and may not predict a hypercoagulable state.
Am J Clin Pathol 2014;142:492-497.

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NATA REVIEW:
Welsh and colleagues investigated thrombelastography (TEG) and conventional coagulation tests (CCT) in 67 retrospectively...
REVIEW by:
J. Stensballe

Published: Oct 2014

Kasivisvanathan R, Abbassi-Ghadi N, Kumar S, et al.

Risk of bleeding and adverse outcomes predicted by thromboelastography platelet mapping in patients taking clopidogrel within 7 days of non-cardiac surgery.
Br J Surg 2014;101:1383-1390.

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NATA REVIEW:
Kasivisvanathan and colleagues open the door a little further to tailored antiplatelet therapy, showing good...
REVIEW by:
J. Stensballe

Published: Oct 2014

Adelmann D, Wiegele M, Wohlgemuth RK, et al.

Measuring the activity of apixaban and rivaroxaban with rotational thrombelastometry.
Thromb Res 2014;134:918-923.

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NATA REVIEW:
Although no routine coagulation monitoring is recommended during treatment with direct factor Xa inhibitors,...
REVIEW by:
D. Faraoni

Published: Aug 2014

Miceli A, Romeo F, Glauber M, de Siena PM, Caputo M, Angelini GD

Preoperative anemia increases mortality and postoperative morbidity after cardiac surgery.
J Cardiothorac Surg 2014;9:137.

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NATA REVIEW:
The authors assessed the impact of preoperative anaemia (according to the WHO definition) on patient outcome...
REVIEW by:
S. Kozek-Langenecker

Published: Jul 2014

Smith GA, Fisher SA, Doree C, Di Angelantonio E, Roberts DJ

Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors.
Cochrane Database Syst Rev 2014;7:CD009532.

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NATA REVIEW:
Iron supplementation in healthy blood donors to reduce donor deferral, iron deficiency and/or anaemia is a matter...
REVIEW by:
R. Moog

Published: Jul 2014

Prick B, Jansen A, Steegers E, et al.

Transfusion policy after severe postpartum haemorrhage: a randomised non-inferiority trial.
BJOG 2014;121:1005-1014.

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NATA REVIEW:
This was a randomised non-inferiority trial of red blood cell transfusion versus no intervention in women with...
REVIEW by:
B. J. Hunt

Published: Jun 2014

Aubron C, Reade MC, Fraser JF, Cooper DJ

Efficacy and safety of fibrinogen concentrate in trauma patients--a systematic review.
J Crit Care 2014;29:471.e11-471.e17

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NATA REVIEW:
Aubron and colleagues performed a systematic review of the use of fibrinogen concentrate in trauma and identified...
REVIEW by:
P. Johansson

Published: May 2014

Yamamoto K, Usui A, Takamatsu J

Fibrinogen concentrate administration attributes to significant reductions of blood loss and transfusion requirements in thoracic aneurysm repair.
J Cardiothorac Surg 2014;9:90.

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NATA REVIEW:
The authors found that an early goal-directed fibrinogen substitution by fibrinogen concentrate was superior...
REVIEW by:
S. Kozek-Langenecker

Published: May 2014

Lozano M, Mahon A, van der Meer PF, et al.

Counting platelets at transfusion threshold levels: impact on the decision to transfuse. A BEST Collaborative - UK NEQAS(H) International Exercise.
Vox Sang 2014;106:330-336.

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NATA REVIEW:
The authors conducted an international laboratory check survey for accuracy of determining platelet counts in...
REVIEW by:
L. T. Goodnough

Published: May 2014

Lundin ES, Johansson T, Zachrisson H, et al.

Single-dose tranexamic acid in advanced ovarian cancer surgery reduces blood loss and transfusions: double-blind placebo-controlled randomized multicenter study.
Acta Obstet Gynecol Scand 2014;93:335-344.

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NATA REVIEW:
This is a well-written prospective randomised study (n = 100) on the effect of a single preoperative...
REVIEW by:
C. Vagianos

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