From the Literature

Published: Jul 2016

Rahe-Meyer N, Levy JH, Mazer CD, et al.

Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy.
Br J Anaesth 2016;117:41-51.

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NATA REVIEW:
In view of the low levels of fibrinogen in various clinical circumstances associated with haemorrhage, replacement...
REVIEW by:
M. Levi

Published: Jul 2016

Barillari G, Londero AP, Brenner B, et al.

Recurrence of venous thromboembolism in patients with recent gestational deep vein thrombosis or pulmonary embolism: Findings from the RIETE Registry.
Eur J Intern Med 2016;32:53-59.

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NATA REVIEW:
This paper looks at the recurrent VTE rate in women who had VTE during pregnancy. As with all data from observational...
REVIEW by:
B. J. Hunt

Published: Jul 2016

Froessler B, Palm P, Weber I, Hodyl NA, Singh R, Murphy EM

The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Ann Surg 2016;264:41-46.

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NATA REVIEW:
In this study, patients with confirmed iron-deficiency anaemia (IDA) scheduled for major abdominal surgery (mostly...
REVIEW by:
M. Muñoz

Published: Jul 2016

Lucas DJ, Ejaz A, Spolverato G, et al.

Packed red blood cell transfusion after surgery: are we "overtranfusing" our patients?
Am J Surg 2016;212:1-9.

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NATA REVIEW:
Using data from a prospective blood management intelligence portal, Lucas and co-authors performed an analysis...
REVIEW by:
T. Frietsch

Published: Jul 2016

Jankowska EA, Tkaczyszyn M, Suchocki T, et al.

Effects of intravenous iron therapy in iron-deficient patients with systolic heart failure: a meta-analysis of randomized controlled trials.
Eur J Heart Fail 2016;18:786-795.

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NATA REVIEW:
Iron deficiency has been observed in a large proportion of patients with chronic heart failure. Most importantly,...
REVIEW by:
D. Faraoni

Published: Jul 2016

Marx G, Schindler AW, Mosch C, et al.

Intravascular volume therapy in adults: Guidelines from the Association of the Scientific Medical Societies in Germany.
Eur J Anaesthesiol 2016;33:488-521.

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NATA REVIEW:
These guidelines on volume therapy should be considered in the bundle concept of patient blood management (PBM)...
REVIEW by:
S. Kozek-Langenecker

Published: Jun 2016

Baharoglu MI, Cordonnier C, Salman RA, et al.

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.
Lancet 2016;387:2605-2613.

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NATA REVIEW:
Essential reading for all. A reminder that however logical a therapy might be (giving platelets to those with...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Larsen TB, Skjøth F, Nielsen PB, Kjældgaard JN, Lip GY

Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.
BMJ 2016;353:i3189.

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NATA REVIEW:
Another article providing real-world data on DOACs compared with warfarin. Helpful also in comparing efficacy...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Daurat A, Roger C, Gris J, et al.

Apheresis platelets are more frequently associated with adverse reactions than pooled platelets both in recipients and in donors: a study from French hemovigilance data.
Transfusion 2016;56:1295-1303.

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NATA REVIEW:
Platelets (PLT) for transfusion can be obtained by apheresis or by whole-blood donation. Pooling of buffy coats...
REVIEW by:
R. Moog

Published: Jun 2016

Klein AA, Collier TJ, Brar MS, et al.

The incidence and importance of anaemia in patients undergoing cardiac surgery in the UK - the first Association of Cardiothoracic Anaesthetists national audit.
Anaesthesia 2016;71:627-635.

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NATA REVIEW:
Klein and colleagues performed a national audit in the UK in order to evaluate the incidence and clinical impact...
REVIEW by:
C. Boer

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