From the Literature

Published: Jan 2016

Majeed A, Goldhaber SZ, Kakkar A, et al.

Bleeding events with dabigatran or warfarin in patients with venous thromboembolism.
Thromb Haemost 2016;115:291-298.

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NATA REVIEW:
Since the approval of dabigatran for stroke prevention in non-valvular atrial fibrillation and for the treatment...
REVIEW by:
F. Bonhomme

Published: Jan 2016

Qureshi SH, Rizvi SI, Patel NN, Murphy GJ

Meta-analysis of colloids versus crystalloids in critically ill, trauma and surgical patients.
Br J Surg 2016;103:14-26.

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NATA REVIEW:
This new meta-analysis comparing colloids to crystalloids in critically ill, trauma and surgical patients confirms...
REVIEW by:
P. Van der Linden

Published: Jan 2016

Tinegate H, Pendry K, Murphy M, et al.

Where do all the red blood cells (RBCs) go? Results of a survey of RBC use in England and North Wales in 2014.
Transfusion 2016;56:139-145.

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NATA REVIEW:
This is a survey reporting the utilization pattern for 75% of the RBC units delivered by the UK NHSBT to hospitals...
REVIEW by:
A. Norgaard

Published: Dec 2015

Siegal DM, Curnutte JT, Connolly SJ, et al.

Andexanet alfa for the reversal of factor Xa inhibitor activity.
N Engl J Med 2015;373:2413-2424

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NATA REVIEW:
The direct factor Xa inhibitors apixaban and rivaroxaban are increasingly used for the prevention and the...
REVIEW by:
D. Faraoni

Published: Dec 2015

Dhabangi A, Ainomugisha B, Cserti-Gazdewich C, et al.

Effect of transfusion of red blood cells with longer vs shorter storage duration on elevated blood lactate levels in children with severe anemia: the TOTAL randomized clinical trial.
JAMA 2015;314:2514-2523.

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NATA REVIEW:
Over the past few years, the "age of blood" has been one of the hot topics discussed regularly during meetings...
REVIEW by:
J. Meier

Published: Dec 2015

Ding YY, Kader B, Christiansen CL, Berlowitz DR

Hemoglobin level and hospital mortality among ICU patients with cardiac disease who received transfusions.
J Am Coll Cardiol 2015;66:2510-2518.

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NATA REVIEW:
This is an interesting investigation which serves to better inform healthcare providers in their clinical decision-making...
REVIEW by:
C. G. Koch

Published: Nov 2015

Refaai MA, Goldstein JN, Lee ML, Durn BL, Milling TJ, Jr., Sarode R

Increased risk of volume overload with plasma compared with four-factor prothrombin complex concentrate for urgent vitamin K antagonist reversal.
Transfusion 2015;55:2722-2729.

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NATA REVIEW:
Immediate reversal of the anticoagulant effect of vitamin K antagonists can be achieved by administration of...
REVIEW by:
M. Levi

Published: Oct 2015

Young P, Bailey M, Beasley R, et al.

Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: the SPLIT randomized clinical trial.
JAMA 2015;314:1701-1710.

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NATA REVIEW:
The SPLIT study, a double-bind, cluster randomised, double-crossover trial that was conducted in 4 ICUs...
REVIEW by:
M. Piagnerelli

Published: Oct 2015

Johansson PI, Rasmussen AS, Thomsen LL

Intravenous iron isomaltoside 1000 (Monofer(®)) reduces postoperative anaemia in preoperatively non-anaemic patients undergoing elective or subacute coronary artery bypass graft, valve replacement or a combination thereof: the PROTECT trial
Vox Sang 2015;109:257-266.

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NATA REVIEW:
This prospective double-blind placebo-controlled randomised single-centre trial reports that, in non-anaemic...
REVIEW by:
P. Van der Linden

Published: Oct 2015

Fowler AJ, Ahmad T, Phull MK, Allard S, Gillies MA, Pearse RM

Meta-analysis of the association between preoperative anaemia and mortality after surgery.
Br J Surg 2015;102:1314-1324.

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NATA REVIEW:
In this meta-analysis, Fowler et al. investigated the impact of preoperative anaemia on postoperative...
REVIEW by:
E. Bisbe

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