From the Literature

Published: Jun 2015

Gregersen M, Borris LC, Damsgaard EM

Postoperative blood transfusion strategy in frail, anemic elderly patients with hip fracture.
Acta Orthop 2015;86:363-372.

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NATA REVIEW:
Gregersen et al. conducted a single-centre (Danish) randomised controlled trial comparing a so-called...
REVIEW by:
S. Lasocki

Published: May 2015

Beyer-Westendorf J, Ebertz F, Forster K, et al.

Effectiveness and safety of dabigatran therapy in daily-care patients with atrial fibrillation. Results from the Dresden NOAC Registry.
Thromb Haemost 2015;113:1247-1257.

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NATA REVIEW:
Dabigatran is increasingly used for stroke prevention in patients with atrial fibrillation. Although the drug...
REVIEW by:
D. Faraoni

Published: May 2015

Goldstein JN, Refaai MA, Milling TJ, Jr., et al.

Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.
Lancet 2015;385:2077-2087.

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NATA REVIEW:
The use of vitamin K antagonists, such as warfarin, has been increasing over the last decades and despite...
REVIEW by:
M. Levi

Published: May 2015

Snyder EL, Stramer SL, Benjamin RJ

The safety of the blood supply ― time to raise the bar.
N Engl J Med 2015;372:1882-1885.

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NATA REVIEW:
The authors describe the aspects of the safety of blood components focusing on pathogen reduction technologies...
REVIEW by:
R. Moog

Published: May 2015

Dias JD, Norem K, Doorneweerd DD, Thurer RL, Popovsky MA, Omert LA

Use of thromboelastography (TEG) for detection of new oral anticoagulants.
Arch Pathol Lab Med 2015;139:665-673.

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NATA REVIEW:
In this experimental study, Dias et al. investigated whether thrombelastography (TEG) could detect and...
REVIEW by:
S. R. Ostrowski

Published: May 2015

Westenbrink BD, Alings M, Connolly SJ, et al.

Anemia predicts thromboembolic events, bleeding complications and mortality in patients with atrial fibrillation: insights from the RE-LY trial.
J Thromb Haemost 2015;13:699-707.

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NATA REVIEW:
In this study, the authors performed a post-hoc analysis of the RE-LY study (a prospective, randomised trial...
REVIEW by:
D. Faraoni

Published: May 2015

Gross I, Seifert B, Hofmann A, Spahn DR

Patient blood management in cardiac surgery results in fewer transfusions and better outcome.
Transfusion 2015;55:1075-1081.

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NATA REVIEW:
Gross et al. compared transfusion and clinical data between the period prior to implementing patient...
REVIEW by:
J.-F. Hardy

Published: Apr 2015

Pisani A, Riccio E, Sabbatini M, Andreucci M, Del Rio A, Visciano B

Effect of oral liposomal iron versus intravenous iron for treatment of iron deficiency anaemia in CKD patients: a randomized trial.
Nephrol Dial Transplant 2015;30:645-652.

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NATA REVIEW:
In this randomised, open-label trial, 99 patients with non-dialysis chronic kidney disease (ND-CKD) and iron...
REVIEW by:
M. Muñoz

Published: Apr 2015

Sentilhes L, Lasocki S, Ducloy-Bouthors AS, et al.

Tranexamic acid for the prevention and treatment of postpartum haemorrhage.
Br J Anaesth 2015;114:576-587.

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NATA REVIEW:
This systematic review provides a good summary of trials evaluating tranexamic acid (TXA) for the prevention...
REVIEW by:
B. J. Hunt

Published: Mar 2015

Carson JL, Sieber F, Cook DR, et al.

Liberal versus restrictive blood transfusion strategy: 3-year survival and cause of death results from the FOCUS randomised controlled trial.
Lancet 2015;385:1183-1189.

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NATA REVIEW:
Carson and colleagues report the long-term results of the FOCUS trial published in 2011. In FOCUS, 2016 elderly...
REVIEW by:
J.-F. Hardy

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