From the Literature

Published: Sep 2001

Molenaar IQ, Legnani C, Groenland TH, et al.

Aprotinin in orthotopic liver transplantation: Evidence for a prohemostatic, but not a prothrombotic, effect.
Liver Transplant 2001;7(10):896-903.

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NATA REVIEW:
This study supports the hypothesis that aprotinin is an anticoagulant which prolongs the aPTT...
REVIEW by:
W. Dietrich

Published: Sep 2001

Ejlersen E, Melsen T, Ingerslev J, Andreasen RB, Vilstrup H

Recombinant activated factor VII (RFVIIa) acutely normalizes prothrombin time in patients with cirrhosis during bleeding from oesophageal varices.
Scand J Gastroenterol 2001;36(10):1081-1085.

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NATA REVIEW:
This is a new open-label study, which showed efficacy of rFVIIa in normalising prothrombin...
REVIEW by:
M. Aldouri

Published: Sep 2001

Hayes JK, Stanley TH, Lind GH, East K, Smith B, Kessler K

A double-blind study to evaluate the safety of recombinant human hemoglobin in surgical patients during general anesthesia.
J Cardiothorac Vasc Anesth 2001;15(5):593-602.

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NATA REVIEW:
The authors evaluated the safety profile of escalating doses of rHb1.1 in patients undergoing...
REVIEW by:
Ph. Van der Linden

Published: Sep 2001

Romero-Castro R, Jimenez-Saenz M, Pellicer-Bautista FJ, et al.

A case of bleeding gastric varices treated with recombinant factor VII.
Rev Esp Enferm Dig 2001;93(10):675-676.

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NATA REVIEW:
This is a case report of a 67-year-old man with severe bleeding due to gastric varices, who...
REVIEW by:

Published: Sep 2001

Tsai AG

Influence of cell-free Hb on local tissue perfusion and oxygenation in acute anemia after isovolemic hemodilution.
Transfusion 2001;41(10):1290-1298.

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NATA REVIEW:
This experimental study shows that, in hamsters, exchange transfusion with polymerized bovine...
REVIEW by:
Ph. Van der Linden; JF Hardy

Published: Sep 2001

Warren BL, Eid A, Singer P, et al.

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial.
JAMA 2001;286(15):1869-1878.

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NATA REVIEW:
An excellent study about the use of AT III in septic patients. Carefully conducted study:...
REVIEW by:
W. Dietrich

Published: Sep 2001

Andreasen AS, Schmidt H, Jarlov JO, Skov R

Autologous transfusion of shed mediastinal blood after coronary artery bypass grafting and bacterial contamination.
Ann Thorac Surg 2001;72(4):1327-1330.

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NATA REVIEW:
A good article to read. Many physicians retransfuse unwashed blood, but most experts prefer washed blood...
REVIEW by:
Gombotz H.

Published: Sep 2001

Wise MW, O’Leary JP

The origins of blood transfusion: the later phase.
Am Surg 2001;67(10):1011-1013.

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NATA REVIEW:
...
REVIEW by:

Published: Sep 2001

Romero Castro R, Barroso Relinque N, Caunedo Alvarez AC, et al.

Use of recombinant factor VII in hepatology.
Rev Esp Enferm Dig 2001;93(10):664-668.

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NATA REVIEW:
This article starts with a general overview on mechanism of action, uses and safety of rFVIIa...
REVIEW by:

Published: Sep 2001

Steinitz D, Harvey EJ, Leighton RK, Petrie DP

Is homologous blood transfusion a risk factor for infection after hip replacement?
Can J Surg 2001;44(5):355-358.

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NATA REVIEW:
Note: It is difficult to ascertain transfusion as a factor entirely separate from co-morbidity. -...
REVIEW by:

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