From the Literature

Published: Sep 2001

Rubin GL, Schofield WN, Dean MG, Shakeshaft AP

Appropriateness of red blood cell transfusions in major urban hospitals and effectiveness of an intervention.
Med J Aust 2001;175(7):354-358.

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NATA REVIEW:
The article describes a too liberal indication for RBC transfusions if recent knowledge on...
REVIEW by:
Kretschmer V.

Published: Sep 2001

Molenaar IQ, Legnani C, Groenland TH, et al.

Aprotinin in orthotopic liver transplantation: Evidence for a prohemostatic, but not a prothrombotic, effect.
Liver Transplant 2001;7(10):896-903.

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NATA REVIEW:
This study supports the hypothesis that aprotinin is an anticoagulant which prolongs the aPTT...
REVIEW by:
W. Dietrich

Published: Sep 2001

Ejlersen E, Melsen T, Ingerslev J, Andreasen RB, Vilstrup H

Recombinant activated factor VII (RFVIIa) acutely normalizes prothrombin time in patients with cirrhosis during bleeding from oesophageal varices.
Scand J Gastroenterol 2001;36(10):1081-1085.

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NATA REVIEW:
This is a new open-label study, which showed efficacy of rFVIIa in normalising prothrombin...
REVIEW by:
M. Aldouri

Published: Sep 2001

Hayes JK, Stanley TH, Lind GH, East K, Smith B, Kessler K

A double-blind study to evaluate the safety of recombinant human hemoglobin in surgical patients during general anesthesia.
J Cardiothorac Vasc Anesth 2001;15(5):593-602.

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NATA REVIEW:
The authors evaluated the safety profile of escalating doses of rHb1.1 in patients undergoing...
REVIEW by:
Ph. Van der Linden

Published: Sep 2001

Romero-Castro R, Jimenez-Saenz M, Pellicer-Bautista FJ, et al.

A case of bleeding gastric varices treated with recombinant factor VII.
Rev Esp Enferm Dig 2001;93(10):675-676.

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NATA REVIEW:
This is a case report of a 67-year-old man with severe bleeding due to gastric varices, who...
REVIEW by:

Published: Sep 2001

Farrant B, Battin M, Roberts A

Outcome of infants receiving in-utero transfusions for haemolytic disease.
N Z Med J 2001;114(1139):400-403.

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NATA REVIEW:
Retrospective analysis of infants receiving in-utero transfusion showing good outcome. No...
REVIEW by:

Published: Aug 2001

Poon MC

Use of recombinant factor VIIa in hereditary bleeding disorders.
Curr Opin Hematol 2001;8(5):312-318.

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NATA REVIEW:
This is another excellent review of the mechanism of action, indications, and various doses...
REVIEW by:
M. Aldouri

Published: Aug 2001

Radder CM, Brand A, Kanhai HH

A less invasive treatment strategy to prevent intracranial hemorrhage in fetal and neonatal alloimmune thrombocytopenia.
Am J Obstet Gynecol 2001;185(3):683-688.

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NATA REVIEW:
Immunoglobulin therapy in pregnant women with antibodies against platelet antigens of the...
REVIEW by:

Published: Aug 2001

Nevo S, Vogelsang GB

Acute bleeding complications in patients after bone marrow transplantation.
Curr Opin Hematol 2001;8(5):319-325.

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NATA REVIEW:
A very important and hopefully stimulating publication. Obviously, our knowledge of the bleeding...
REVIEW by:
V. Kretschmer.

Published: Aug 2001

Toyoda H, Fukuda Y, Nakano I, et al.

TT virus genotype changes frequently in multiply transfused patients with hemophilia but rarely in patients with chronic hepatitis C and in healthy subjects.
Transfusion 2001;41(9):1130-1135.

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NATA REVIEW:
TTV seems not to have clinical relevance. However, the publication is very important since...
REVIEW by:
V. Kretschmer.

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