From the Literature

Published: Aug 2001

Martinowitz U, Kenet G, Segal E, et al.

Recombinant activated factor VII for adjunctive hemorrhage control in trauma.
J Trauma 2001;51(3):431-438.

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NATA REVIEW:
This is a relatively new area for using rFVIIa, which is to treat uncontrolled haemorrhage...
REVIEW by:
M. Aldouri

Published: Aug 2001

van Kamp IL, Klumper FJC, Bakkum RS, et al.

The severity of immune fetal hydrops is predictive of fetal outcome after intrauterine treatment.
Am J Obstet Gynecol 2001;185(3):668-673.

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NATA REVIEW:
This retrospective study shows that the severity of immune fetal hydrops and the response...
REVIEW by:
Kretschmer V.

Published: Aug 2001

Vichinsky EP, Luban NLC, Wright E, et al.

Prospective RBC phenotype matching in a stroke-prevention trial in sickle cell anemia: a multicenter transfusion trial.
Transfusion 2001;41(9):1086-1092.

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NATA REVIEW:
For a transfusionist from West/North Europe, the results are predictable and the conclusion...
REVIEW by:
V. Kretschmer.

Published: Aug 2001

Chuansumrit A, Sri-Udomporn N, Srimuninnimit V, Juntarukha R

A single high dose of recombinant factor VIIa combining adjuvant therapy for controlling bleeding episodes in haemophiliacs with inhibitors.
Haemophilia 2001;7(5):532-534.

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NATA REVIEW:
A single dose of rFVIIa (150-180 μg/kg) was used to treat five muscle/joint bleeds and...
REVIEW by:
M. Aldouri

Published: Aug 2001

Wilkes MM, Navickis RJ

Patient survival after human albumin administration. A meta-analysis of randomized, controlled trials.
Ann Intern Med 2001;135(3):149-64.

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NATA REVIEW:
Two commentaries of this article have been published in the June 2002 issue of the Canadian...
REVIEW by:

Published: Jul 2001

Jurlander B, Thim L, Klausen NK, et al.

Recombinant activated factor VII (RFVIIa): Characterization, manufacturing, and clinical development.
Semin Thromb Hemostasis 2001;27(4):373-383.

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NATA REVIEW:
A good overall review on the characterization, mechanism of action, and preclinical and...
REVIEW by:
M. Aldouri

Published: Jul 2001

Blatt J, Gold SH, Wiley JM, Monahan PE, Cooper HC, Harvey D

Off-label use of recombinant factor VIIa in patients following bone marrow transplantation.
Bone Marrow Transplant 2001;28(4):405-407.

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NATA REVIEW:
This is a report on off-label extended use of rFVIIa in managing pulmonary, vesical and GI...
REVIEW by:
M. Aldouri

Published: Jul 2001

Erhardtsen E, Nilsson P, Johannessen M, Thomsen MS

Pharmacokinetics and safety of FFR-rFVIIa after single doses in healthy subjects.
J Clin Pharmacol 2001;41(8):880-885.

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NATA REVIEW:
This is a double-blind placebo controlled dose escalation trial evaluating efficacy and safety...
REVIEW by:
M. Aldouri; J. Ingerslev

Published: Jul 2001

Frere MC, Rapaille A, Bouillenne C, Gerard C, Sondag D, Verhees A

Analysis of 516 reaction reports after transfusion of blood cell components.
Transfus Clin Biol 2001;8(4):333-342.

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NATA REVIEW:
The article gives data on transfusion reactions that are not conclusive. There is no doubt...
REVIEW by:
Kretschmer V.

Published: Jul 2001

Bergler W, Huber K, Hammerschmitt N, Hormann K

Tonsillectomy with argon plasma coagulation (APC): Evaluation of pain and hemorrhage.
Laryngoscope 2001;111(8):1423-1429.

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NATA REVIEW:
The use of argon beam coagulation provides advantages both in reducing blood loss and decreasing...
REVIEW by:
R. K. Spence

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