Analysis of 516 reaction reports after transfusion of blood cell components.

The article gives data on transfusion reactions that are not conclusive. There is no doubt about the reduction of non-hemolytic transfusion reactions in chronically transfused patients when using leukodepleted cellular blood components. Finding no difference in the incidence of transfusion reactions between leukodepleted and non-leukodepleted RBCs is contrary to daily experience. However, it is true that universal leukodepletion does not reduce transfusion reactions as significantly as directed leukodepletion (chronically transfused patients, patients with a history of transfusion reactions, etc.).

– V. Kretschmer.