Selective aortic arch perfusion with hemoglobin-based oxygen carrier-201 for resuscitation from exsanguinating cardiac arrest in swine.

The important message in this case is that a hemoglobin-based oxygen carrier was able to restore viable cardiovascular function after exsanguinating cardiac arrest in a swine model of liver injury with profound hemorrhagic shock. Nonetheless, the reader is left with many questions. What effect(s) of the hemoglobin solution was responsible for the favorable outcome observed―a vasopressor effect or increased oxygen transport? How feasible is SAAP in patients with blunt traumatic cardiac arrest?

– J.-F. Hardy.

Tagged blood substitutes, heart, HEMORRHAGE, hemorrhagic shock, shock, traumatic shock

NATA: Network for the advancement of Patient Blood Management, Haemostasis and Thrombosis

MISSION: Providing a multidisciplinary forum for dialogue between haematologists, transfusion medicine specialists, anaesthesiologists, intensive care and emergency physicians, surgeons, perfusionists, nurses, biomedical scientists and ther heathcare professionals.

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Selective aortic arch perfusion with hemoglobin-based oxygen carrier-201 for resuscitation from exsanguinating cardiac arrest in swine.

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