Nov
2001

Successful outcome of a cirrhotic patient with postoperative haematuria treated with a single high dose of recombinant factor VIIa.

Lucia JF, Aguilar C, Orna E, et al.
Haemophilia 2001;7(6):600-602.
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Etiology of bleeding in patients with liver disease is multifactorial, and there has been variable response to treatment with rFVIIa, although correction of prolonged prothrombin time in such patients has been reported. This is a case report of a cirrhotic patient who developed intractable hematuria following urinary bladder tumor resection in spite of transfusion of blood products and repeat surgery. He eventually responded to a single high dose of rFVIIa. This case report strengthens the potential benefit of rFVIIa in patients with liver disease and bleeding.


– M. Aldouri.