Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhage.

Gerotziafas GT, Zervas C, Gavrielidis G, et al.
Am J Hematol 2002;69(3):219-222.
NATA Rating :
Review by : M. Aldouri
NATA Review
This article reports 2 patients with severe thrombocytopenia and severe hemorrhage which did not respond to standard therapy and platelet transfusion, but responded quickly to administration of a single dose of rFVIIa. The first patient had Waldenstoms macroglobulinemia and immune thrombocytopenia, and the second one had acute lymphoblastic leukemia. No adverse effects for rFVIIa were reported.

– M. Aldouri.

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