Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors.
O’Connell N, McMahon C, Smith J, et al.
Br J Haematol 2002;116(3):632-635.
NATA Rating :
Review by : Aldouri M
This study reports the effective use of rFVIIa in covering 20 surgical procedures in 12 patients with hemophilia VIII with high inhibitors, in addition to treating 6 episodes of severe bleeding in 3 patients successfully. All but one of the surgical procedures were insertion or removal of a central venous access device. This paper again proves the efficacy and safety of rFVIIa in treating hemophilia patients with inhibitors.
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