Mar
2002
Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors.
Br J Haematol 2002;116(3):632-635.
NATA Rating :
Review by : Aldouri M
NATA Review
This study reports the effective use of rFVIIa in covering 20 surgical procedures in 12 patients with hemophilia VIII with high inhibitors, in addition to treating 6 episodes of severe bleeding in 3 patients successfully. All but one of the surgical procedures were insertion or removal of a central venous access device. This paper again proves the efficacy and safety of rFVIIa in treating hemophilia patients with inhibitors.
– M. Aldouri.