Transfusion in premature infants impairs production and/or release of red blood cells, white blood cells and platelets.
The author concludes that suppression of erythro-, leuko- and thrombopoiesis within 48 hours after transfusion decreases the amount of precursor cells in the peripheral blood. This is a very important […]
The theory and practice of bloodless surgery.
A very thorough overview of all aspects of blood-sparing methods. – V. Kretschmer
Economic evaluation of a randomized clinical trial of haemodilution with cell salvage in aortic surgery.
This article brings important information about the cost-effectiveness of acute normovolemic hemodilution and intraoperative cell salvage when used in major vascular surgery. – P. Van der Linden
Effects of normovolaemic haemodilution on middle cerebral artery blood flow velocity and oxygen delivery.
This experimental study showed that acute isovolemic hemodilution to a hematocrit of 20% resulted in a decreased oxygen delivery to the brain as the increase in cerebral blood flow did […]
Mechanical methods of reducing blood transfusion in cardiac surgery: randomised controlled trial.
This study assesses the effectiveness of intraoperative cell salvage with or without normovolemic hemodilution in patients undergoing elective coronary artery bypass surgery. The results are not particularly new and the […]
Platelet transfusions in children: results of a randomized, prospective, crossover trial of plasma removal and a prospective audit of WBC reduction.
Disappointing and rather surprising results. The lower incidence of transfusion reactions (TR) in children is not surprising since the referred frequency of TR in adults (up to 37% from literature) […]
Retrograde autologous priming of the cardiopulmonary bypass circuit reduces blood transfusion after coronary artery surgery.
This article confirms previous studies showing that a reduction of the bypass circuit priming volume can be associated with a reduction in allogeneic blood use. This beneficial effect is related […]
Perioperative hemodilution.
This is an interesting review article on the use of acute normovolemic hemodilution as part of a blood conservation strategy in patients undergoing elective surgery. – P. Van der Linden
Massive blood transfusion in the elective surgical setting.
Nice overview, but inconsistency between recommendations in the figures and in the text. – V. Kretschmer
Increased rate of infection associated with transfusion of old blood after severe injury.
This is a very important topic. All logical aspects would seem to suggest that stored cellular blood components have an immune suppressive effect. However, it is questionable whether this study […]