Aug
2002

Recombinant factor VIIa after aortic valve replacement in a patient with osteogenesis imperfecta.

Kastrup M, von Heymann C, Hotz H, et al.
Ann Thorac Surg 2002;74(3):910-912.
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This is another case report on the efficacy of Novoseven in controlling severe bleeding in cardiac surgery. Post-operative bleeding continued in spite of the use of blood products and aprotinin infusion, but stopped after a single dose of rFVIIa. Coronary catheterization performed after giving rFVIIa showed good aortic prosthetic function and no alteration in the coronary arteries.

– M. Aldouri