Recombinant factor VIIa after aortic valve replacement in a patient with osteogenesis imperfecta.

This is another case report on the efficacy of Novoseven in controlling severe bleeding in cardiac surgery. Post-operative bleeding continued in spite of the use of blood products and aprotinin infusion, but stopped after a single dose of rFVIIa. Coronary catheterization performed after giving rFVIIa showed good aortic prosthetic function and no alteration in the coronary arteries.

– M. Aldouri