Intracerebral hemorrhage: natural history and rationale of ultra-early hemostatic therapy.

This is an interesting and challenging area for the use of rFVIIa at early stages of hemorrhagic stroke in order to prevent growth of hematoma which occurs in this type of strokes. The paper gives an excellent review on the pathogenesis and management of intracerebral hemorrhage, and the potential role of rFVIIa. A randomized placebo controlled study is ongoing to address this therapy.

– M. Aldouri