Nov
2002

Mild hypothermia has minimal effects on the tolerance to severe progressive normovolemic anemia in swine.

Perez de Sa V, Roscher R, Cunha-Goncalves D, Larsson A, Werner O
Anesthesiology 2002;97(5):1189-1197.
NATA Rating :
Review by : Van der Linden P, Messmer K
NATA Review
This experimental study performed in anesthetized pigs reports that hypothermia to 32C did not really improve tolerance to acute dilutional anemia as reflected by a non significant change in the critical hemoglobin value (i.e., the value of hemoglobin below which oxygen consumption becomes supply-dependent). Although not directly applicable to the clinical setting, these observations could have important implications in the management of severe anemic patients.

– Philippe Van der Linden