Sequential treatment with bolus and continuous infusion of recombinant factor VIIa for hip arthroplasty in a patient with haemophilia A and inhibitor.

This is a case report on a hemophilia VIII patient with high titer inhibitor who underwent total hip replacement and treatment with rFVIIa. rFVIIa was given as bolus treatment for 5 days, followed by continuous infusion with reduced doses for 12 more days. The patient made excellent recovery. The authors claim that using rFVIIa in this way saves 30% on the cost of treatment.

– Maadh Aldouri