Use of perflubron emulsion to decrease allogeneic blood transfusion in high-blood-loss non-cardiac surgery: results of a European phase 3 study.
– Jean-Franois Hardy
This prospective randomized study demonstrates the efficacy of a perfluorocarbon-based oxygen carrier to reduce exposure to allogeneic blood components when combined to acute normovolemic hemodilution in patients undergoing major surgery associated with high blood loss. This study also highlights the fact that the successful use of these products will require education of healthcare professionals to familiarize them with new concepts and physiology.
– Philippe Van der Linden