May
2003

The use of acute normovolemic hemodilution in patients undergoing cardiac surgery.

Jovic ME, Calija BM, Radomir BJ, et al.
Cardiovasc Surg 2003;11(3):201-205.
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In this observational study, the authors report their experience with the use of acute normovolemic hemodilution in cardiac surgery patients.

– Philippe Van der Linden

This article convincingly shows that ANH in patients undergoing cardiac surgery significantly reduces the need for allogeneic blood transfusion. Autologous blood removed ranged from 1 (70%) to 2-5 (30% of patients) units into plastic bags containing citrate. Simultaneously Ringer Lactate and gelatin or dextran were infused to maintain normovolemia. The transfusion trigger was set at 22% hematocrit. Despite this conservative and therefore safe transfusion trigger, allogeneic transfusion was avoided in 46% of patients during hospital stay. In addition the authors demonstrate that the use of ANH has clearly resulted in financial savings, a very important issue in Yugoslavia.

– Konrad Messmer