Antidotes to haemorrhage: recombinant factor VIIa.

Kessler CM
Best Pract Res Clin Haematol 2004;17:183-197.
NATA Rating :
Review by : M. Aldouri
NATA Review

This is an excellent and comprehensive review on the use of rFVIIa, its mechanism of action and various indications for its use in controlling bleeding in congenital and acquired coagulation disorders: factors VIII or IX deficiencies, oral vitamin K antagonists overdose, direct and indirect thrombin inhibitors, platelet disorders, and bleeding due to surgery or trauma.

– Maadh Aldouri

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