Nov
2004

The use of recombinant activated factor VII in three patients with central nervous system hemorrhages associated with factor VII deficiency.

Huang WY, Kruskall MS, Bauer KA, Uhl L, Shaz BH
Transfusion 2004;44(11):1562-1566.
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This is a case report on 3 patients who suffered traumatic or surgical central nervous system bleeding associated with moderate factor VII deficiency and were successfully treated with rFVIIa after failure to respond to vitamin K and FFP. The etiology for factor VII deficiency is thought to be acquired, but factor VII was subsequently measured only in one patient after recovery and found to be normal.

– Maadh Aldouri