Dec
2004

Hemostatic effect of activated recombinant factor VIIa in Bernard-Soulier syndrome: studies in an in vitro model.

Tonda R, Galan AM, Pino M, Lozano M, Ordinas A, Escolar G
Transfusion 2004;44(12):1790-1791.
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This is a letter describing an experiment in which rFVIIa was mixed with platelets from a patient with Bernard-Soulier syndrome. Platelet function (aggregation) was shown to improve, in addition to increased fibrin and thrombin generation.

– Maadh Aldouri