Feb
2005

The use of recombinant factor VIIa in a patient with essential thrombocythaemia with uncontrolled surgical bleeding.

Cervera JS, Mena-Duran AV, Piqueras CS
Thromb Haemost 2005;93(2):383-384.
NATA Rating :
Review by : M. Aldouri
NATA Review

Recombinant factor VIIa has been found to be effective in controlling bleeding associated with inherited and acquired platelet dysfunction, such as thromboasthenia and renal failure. In this case report, rFVIIa was successful in controlling bleeding associated with essential thrombocythemia in a patient who underwent hysterectomy and failed to respond to blood products and EACA. However, it may not have been necessary to continue rFVIIa for one week.

– Maadh Aldouri