Increasing hematocrit above 28% during early resuscitative phase is not associated with decreased mortality following severe traumatic brain injury.

Flckiger C, Bchir M, Brenni M, et al.
Acta Neurochir (Wien) 2009; Dec 24 [Epub ahead of print].
NATA Rating :
Review by : C. Quentin
NATA Review

In this retrospective study of patients with traumatic brain injury (TBI), the impact of two hematocrit levels (< or ≥ 28%) on morbidity and mortality (Glasgow outcome scale) in the immediate postoperative period was analysed. The authors observed that increasing hematocrit above 28% in TBI patients was not associated with improved or worsened outcome. The best transfusion management in TBI patients is still undetermined. – Charlotte Quentin and Jean-Franois Hardy

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