Therapeutic efficacy of platelet transfusion in patients with acute leukemia: an evaluation of methods.

Apelseth TO, Bruserud O, Wentzel-Larsen T, Hervig T
Transfusion 2009; Dec 18 [Epub ahead of print].
NATA Rating :
Review by : P. Rebulla
NATA Review

The authors of this study report that the thromboelastogram value ‘maximal amplitude’ – an indicator of platelet function – could provide predictive information on functionality of transfused platelets and bleeding risk in leukemia. Carefully standardized thromboelastography could therefore represent a new tool to determine platelet transfusion requirements in oncology/hematology.

– Paolo Rebulla

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