Red blood cell transfusion is associated with infection and extracerebral complications after subarachnoid hemorrhage.

Levine J, Kofke A, Cen L, et al.
Neurosurgery 2010;66(2):312-318.
NATA Rating :
Review by : C. Quentin
NATA Review

In this retrospective study of 421 patients with subarachnoid hemorrhage (SAH) in the intensive care unit, the relationship between red blood cell transfusion (RBCT) and extracerebral complications and infection was examined. RBCT was independently associated with medical complications (OR 1.8 [1.1-3]; p=0.02), infections (OR 2.8 [1.7-4.5]; p<0.001), the need for and duration of mechanical ventilation (OR 2.8 [1.5-5.1]; p<0.001) and length of stay (p<0.001). However, whether RBCT is a cause of medical complications or simply a marker of disease severity requires further study. – Charlotte Quentin and Jean-Franois Hardy

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