Preoperative very short-term, high-dose erythropoietin administration diminishes blood transfusion rate in off-pump coronary artery bypass: a randomized blind controlled study.

Weltert L, DAlessandro S, Nardella S, et al.
J Thorac Cardiovasc Surg 2009; Dec 28 [Epub ahead of print].
NATA Rating :
Review by : P. Van der Linden
NATA Review

This prospective randomized single-blind study reported that transfusion requirement in patients undergoing off-pump cardiac surgery could be reduced by erythropoiesis stimulation in the immediate preoperative period. This study, however, did not possess the power to adequately evaluate the safety of preoperative short-term high-dose recombinant human erythropoietin administration.

– Philippe Van der Linden

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