Jan
2010
Hemostatic and electrolyte effects of hydroxyethyl starches in patients undergoing posterior lumbar interbody fusion using pedicle screws and cages.
Spine (Phila Pa 1976) 2010; Jan 12 [Epub ahead of print].
NATA Rating :
Review by : S. Kozek-Langenecker
NATA Review
Confirming previous studies, dilutional coagulopathy was more pronounced after 15 ml/kg slowly degradable HES (Hextend) vs. rapidly degradable HES (Voluven) and postoperative transfusion rate at a high hematocrit trigger was higher after Hextend. Future studies should implement a functional fibrinogen assay (e.g. FIBTEM) and individualize the dose of fluid therapy.
– Sybille Kozek-Langenecker