Thromboelastometrically guided transfusion protocol during aortic surgery with circulatory arrest: a prospective, randomized trial.

Girdauskas E, Kempfert J, Kuntze T, et al.
J Thorac Cardiovasc Surg 2010;140(5):1117-1124.
NATA Rating :
Review by : S. Kozek-Langenecker
NATA Review

In this randomized controlled trial during aortic surgery, requirements for allogeneic blood, prothrombin complex concentrates and recombinant factor VIIa were reduced in the ROTEM-guided group, while fibrinogen concentrate usage was comparable between groups. Aside from improved quality of care by implementing a strict and pathophysiology-driven management protocol, health costs may be reduced.

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