This observational cohort study of 102,470patients undergoing primary isolated CABG with cardiopulmonary bypass during calendar year 2008 at 798sites in the United States reports a wide variability in the rate of transfusion of blood components. Hospital characteristics and case mix explained only 11 and 20% of the variation, respectively. These results clearly emphasize the necessity to develop specific blood conservation programs adapted to each hospital in order to improve blood transfusion practice.

– Philippe Van der Linden