Relevance of colloid oncotic pressure regulation during neonatal and infant cardiopulmonary bypass: a prospective randomized study.

This prospective randomized study evaluated the influence of two different colloid osmotic pressure (COP) regulatory strategies on postoperative weight gain and clinical outcomes in neonates and infants undergoing cardiac surgery with cardiopulmoary bypass. No major clinically relevant difference was reported between the two groups, but the difference in on-bypass COP between the 2 groups was very small (1.5 mmHg). A higher difference in COP might have resulted inh more clinically relevant differences, as reported by other authors in adults and children.

– Philippe Van der Linden