Effects of a comprehensive blood-sparing approach using body weight-adjusted miniaturized cardiopulmonary bypass circuits on transfusion requirements in pediatric cardiac surgery.

Redlin M, Habazettl H, Boettcher W, et al.
J Thorac Cardiovasc Surg 2012; Feb 1 [Epub ahead of print].
NATA Rating :
Review by : H. Morimatsu
NATA Review

This study showed that a comprehensive blood-sparing approach while minimizing the priming volume of the CPB circuit resulted in a 24.7% avoidance rate of perioperative transfusion in infants <16 kg body weight. The results suggest that the less pump prime volume, the less dilution, and the less transfusion. However, this strategy requires further prospective evaluation. – Hiroshi Morimatsu

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