Nov
2013

Effectiveness of tranexamic acid on blood loss in patients undergoing elective cesarean section: randomized clinical trial.

Abdel-Aleem H, Alhusaini TK, Abdel-Aleem MA, Menoufy M, Gulmezoglu AM
J Matern Fetal Neonatal Med 2013;26:1705-1709.
NATA Rating :
Review by : B. J. Hunt
NATA Review

This study randomized over 700 women undergoing elective Cesarean section to receive 1 gram of tranexamic acid versus nothing. Blood loss was significantly reduced — 510 (SE 7.7) versus 242 (SE 6.8) mL — and the post-procedure fall in hemoblogin was less in those receiving tranexamic acid. Rates of post-procedure thrombosis were not formally assessed.

– Beverley J. Hunt