Ranking the effectiveness of autologous blood conservation measures through validated modeling of independent clinical data.

Based on available clinical studies, efficacy (maximal tolerable blood loss) and effectiveness (gain in RBC mass) were calculated in a mathematical model for acute normovolemic hemodilution (ANH), intraoperative blood salvage (IBS), and preoperative autologous deposit (PAD). ANH showed no blood-saving capacity. PAD was sufficient under certain circumstances, namely when erythropoiesis is adequate, and time intervals and donated volume appropriate. Cell salvage proved most efficacious and effective.

This is a well-conducted, important study to underline the major role of cell salvage in blood management.

– Ernil Hansen