The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the treatment of anemia and iron deficiency in adult patients with heart disease, based on a systematic review report in the same issue of the journal (Kansagara D et al, Ann Intern Med 2013;159:746-57; see Nataonline comment). The ACP recommends a restrictive transfusion strategy but this is classified as a weak recommendation with low quality evidence. The second recommendation is against the use of erythropoiesis-stimulating agents in patients with congestive heart failure or coronary heart disease. This recommendation is rated as strong and based on moderate quality evidence.

– Jeffrey L. Carson