Apr
2014

Distinct immunologic effects of different intravenous iron preparations on monocytes.

Fell LH, Zawada AM, Rogacev KS, Seiler S, Fliser D, Heine GH
Nephrol Dial Transplant 2014;29:809-822.
NATA Rating :
Review by : M. Auerbach
NATA Review

This is unique but actually supports the increased oxidative stress markers seen with iron sucrose compared to the other formulations where the iron is bound more tightly by the carbohydrate core. This is a complicated, basic research study. The conclusions are, however, well stated and provocative but until clinical relevance becomes known, it will fall into the same category as the oxidative stress studies have: interesting, provocative and of questionable clinical relevance.

– Michael Auerbach