Aug
2014

Post-traumatic immunosuppression is reversed by anti-coagulated salvaged blood transfusion: deductions from studying immune status after knee arthroplasty.

Islam N, Whitehouse M, Mehendale S, et al.
Clin Exp Immunol 2014;177:509-520.
NATA Rating :
Review by : D. Thomas
NATA Review

This article further explains the potential benefit of reinfused autoogous blood. Since the authors published their previous article in the Lancet (Gharehbaghian A et al. Lancet 2004;363:1025-30), very few researchers have confirmed the original findings.This publication, however, takes that theme further with a very detailed account of the immunological changes that result from the reinfusion of autologous blood transfusion. Probably the most interesting finding is the difference in upregulation of immune status with anticoagulated autologous blood when compared with non-anticoagulated autologous blood. The story continues…

– Dafydd Thomas

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