Transfusion policy after severe postpartum haemorrhage: a randomised non-inferiority trial.

Prick B, Jansen A, Steegers E, et al.
BJOG 2014;121:1005-1014.
NATA Rating :
Review by : B. J. Hunt
NATA Review

This was a randomised non-inferiority trial of red blood cell transfusion versus no intervention in women with acute anaemia after postpartum haemorrhage. The primary outcome was physical fatigue 3 days postpartum. Statistical non-inferiority was not reached and some of the women in the no-intervention group did receive transfusions. The authors argue that they set an unreasonable non-inferiority target. Overall, the paper does suggest that non-transfusion is a possible option in this setting and further research is justified.

– Beverley J. Hunt

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