The authors investigated the in vitro effect of dabigatran on whole blood thromboelastography (TEG) and its reversal by recombinant activated factor VII (rFVIIa) and 4-factor prothrombin complex concentrate (PCC). Dabigatran changed all TEG parameters. There was little effect with PCC and some reversal with rFVIIa.

This paper adds to the literature on dabigatran reversal.

– Beverley J. Hunt