The authors performed a proof-of-principle pilot study indicating that point-of-care platelet function testing predicts relevant blood loss after CABG in clopidogrel-treated patients. ROC analyses identified a specific threshold P2Y12 inhibitor level.
This publication supports an individualised perioperative management strategy: instead of waiting a fixed number of days after clopidogrel withdrawal, a sensitive laboratory result may help determine the optimal timing of surgery.
– Sibylle Kozek-Langenecker
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