Impact of a Patient Blood Management monitoring and feedback programme on allogeneic blood transfusions and related costs.
While Patient Blood Management (PBM) is becoming a new standard worldwide with evidence-based and expert consensus guidelines to promote the three PBM pillars, measuring the performance of these efforts remains […]
Obstetric intra-operative cell salvage: a review of an established cell salvage service with 1170 re-infused cases.
This is a retrospective report of 10 years of obstetrical cell salvage use in a single hospital. The authors report on 1170 patients who had a median of 231 mL of blood […]
Multimodal patient blood management program based on a three-pillar strategy: a systematic review and meta-analysis.
This systematic review and meta-analysis focused on the implementation of a comprehensive PBM approach. Studies included had to address at least one recognised PBM modality per pillar. Data for 235,779 surgical […]
2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.
There is growing evidence that patient blood management (PBM) is becoming “standard of care” in major surgery associated with high blood loss, particularly in cardiac surgery. These guidelines are the […]
The impact of a multidisciplinary blood conservation protocol on patient outcomes and cost after cardiac surgery.
This before-and-after study confirms that a standardised intraoperative blood conservation programme including expanded use of cell salvage, extensive adoption of acute isovolemic haemodilution and routine use of retrograde autologous priming […]
Improved outcomes and reduced costs associated with a health-system-wide patient blood management program: a retrospective observational study in four major adult tertiary-care hospitals.
“Randomised controlled trials (RCTs) are the de facto standard for answering clinical questions, delivering the highest grade of evidence available.” What sounds logical at first sight for many scientific problems […]
Patient blood management bundles to facilitate implementation.
How to cook a patient blood management programme! In this ‘position paper’, a group of well-known PBM experts offers us a how-to guide for those looking to implement PBM programmes. […]
Acute normovolemic hemodilution reduces allogeneic red blood cell transfusion in cardiac surgery: a systematic review and meta-analysis of randomized trials.
This meta-analysis, which includes 29 randomised controlled trials for a total of 2439 patients, evaluates the effectiveness of acute normovolemic haemodilution (ANH) to reduce the number of allogeneic red blood cell (RBC) […]
Revisiting acute normovolemic hemodilution and blood transfusion during pediatric cardiac surgery: a prospective observational study.
Children undergoing cardiac surgery with cardiopulmonary bypass (CPB) are at high risk of being exposed to relatively large volumes of allogeneic blood products. If blood transfusion can be life-saving in […]
Very low rate of patient-related adverse events associated with the use of intraoperative cell salvage.
This retrospective review confirms that the use of cell salvage intraoperatively is safe, with a rate of patient-related adverse event varying between 0 and 0.006%. Although this very low incidence […]
Washed cell salvage in surgical patients: A review and meta-analysis of prospective randomized trials under PRISMA.
In the absence of large randomised trials, meta-analyses are a useful tool to assess whether a technique is clinically beneficial. This meta-analysis by Meybohm et al. provides further support to […]
Intra-operative cell salvage in cardiac surgery may increase platelet transfusion requirements: a cohort study.
This article gives the results of an observational study that used a historical cohort of patients as a control group. This of course can cause a myriad of confounding issues. […]
Patient blood management in cardiac surgery results in fewer transfusions and better outcome.
Gross et al. compared transfusion and clinical data between the period prior to implementing patient blood management (PBM) (2006–2007) and after implementation of a PBM programme (2007–2012). The study suffers […]
Practice guidelines for perioperative blood management: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Management.
These Practice Guidelines update “Practice Guidelines for Perioperative Blood Transfusion and Adjuvant Therapies: An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant […]
Effects of the Sangvia blood collection system on patients undergoing elective hip surgery.
Teeztmann et al. conducted a randomised controlled study where 164 patients received either autologous salvaged blood collected using the Sangvia™ Blood Salvage System or allogeneic red cell concentrates if transfusion was […]