The ALBIOS study, a multicentre open-label randomised controlled trial performed in 100 Italian ICUs, evaluated the effect of albumin supplementation on 28-day mortality in patients with severe sepsis or septic shock. […]
This study was conducted over one year and included 479 patients requiring ICU stay after scheduled major surgery. The authors concluded that higher fluid balance during surgery increased morbidity (longer ICU […]
This new mulitcenter, randomized on the reason for admission (sepsis, trauma, hypovolemia from other causes), but unblinded study compared the effects of crystalloids versus hypo- or hyperoncotic colloids on mortality […]
Among other major methodological limitations, unclear group allocations (e.g. exposure to a mixture of various fluids in all groups, even more HES as pump prime in the crystalloid group, median […]
Van der Linden and colleagues completed a small randomized double-blind controlled trial in children aged 2-12 years undergoing elective surgery with cardiopulmonary bypass for congenital cardiac disease; 29 patients were allocated to […]
This review included 42 randomized controlled trials (for a total of 11,399 patients): 19 studies from a previous review and 23 new studies, in which hydroxyethyl starch (HES) solutions were compared to an alternative […]
Vesicle encapsulated hemoglobin solutions have been under development in Japan for several decades. Many experimental studies support the perception that this technology may ultimately lead to the development of a […]
This prospective randomized single-blind study reported that the use of hydroxyethyl starch 130/0.4 (HES 130/0.4) prepared in a saline solution (0.9% NaCl) for cardiopulmonary bypass priming is associated with a […]
As expected, this randomized, double-blind, single center study showed a significant decrease of hyperchloremic metabolic acidosis in patients with brain injury (brain trauma with CGS ≤ 8 or subarachnoid haemorrhage […]
This meta-analysis included 17 studies (1230 patients) that evaluated the renal effects of 6% waxy maize-derived hydroxyethyl starch 130/0.4 (in 0.9% NaCl) in surgical patients, with the exception of patients […]
This meta-analysis assessed the association of different hydroxyethyl starch solutions with mortality and acute kidney injury in an heterogenous population of critically ill patients who required volume resuscitation. When excluding […]
The authors sought to determine whether fluid resuscitation of acutely ill patients with hydroxyethyl starch (HES) compared with other resuscitation fluids results in a difference in the relative risk of […]
In this well-designed review and meta-analysis, the authors assess the available evidence on the use of hydroxyethyl starch 130/0.38-0.45 versus crystalloid or albumin in patients with severe sepsis. After reviewing […]
Several recent meta-analyses have suggested that hydroxyethyl starches (HES) may be associated with an increase in mortality and in the need for renal replacement therapy (RRT), specially in patients admitted […]
Recent meta-analyses have compared the effect of HES with comparators on the risk of mortality in critically ill patients. These have looked carefully at the risk of methodological bias and […]
NATA: Network for the advancement of Patient Blood Management, Haemostasis and Thrombosis
MISSION: Providing a multidisciplinary forum for dialogue between haematologists, transfusion medicine specialists, anaesthesiologists, intensive care and emergency physicians, surgeons, perfusionists, nurses, biomedical scientists and ther heathcare professionals.
I am text block. Click edit button to change this text. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.
