Surgical patients may be at high risk of venous thromboembolism (VTE). SARS‐CoV‐2 infection has been shown to increase this risk. In this huge international, multicentre, prospective cohort study of elective and emergency […]
Current approaches to trauma resuscitation focus on the timely control of bleeding and correction of trauma-induced coagulopathy using the administration of haemostatic therapy. Over the past decade, targeted and individualized […]
This observationnal study has included 240 consecutive patients with confirmed severe acute respiratory syndrome coronavirus 2 infection admitted to one of three hospitals. One-hundred nine critically ill COVID 19 patients admitted […]
In this retrospective, observational study, Waldén et al. describe the occurrence of thromboembolic events and mortality in cardiac surgery patients, depending on whether the patient had received fibrinogen supplementation. The […]
In this multicentre, parallel-group, open-label, randomised trial, the authors compared the efficacy and safety of rivaroxaban versus standard anticoagulants in children 0-17 years with venous thromboembolism. Across 107 paediatric hospitals […]
The Platelets for Neonatal Thrombocytopenia (PlaNeT-2) trial, a multicentre randomised clinical trial, found an unexpected overall benefit of a prophylactic platelet transfusion threshold of 25 x 10^9/L compared to 50 x 10^9/L for […]
Early plasma transfusion is believed to improve maternal outcomes in postpartum haemorrhage (PPH) because it could theoretically prevent or treat coagulopathy occurring among women treated for persistent PPH. However, as […]
This important study by McNamara et al. reports on four years of observational data from a large UK hospital and tertiary referral unit, following the introduction of a rotational thromboelastometry-guided […]
This study was designed to examine whether tranexamic acid, which is a well-established therapy to reduce postoperative bleeding, is associated with adverse events in patients at high risk for a […]
The authors performed a pilot study comparing topical versus intravenous administration of tranexamic acid. Given the heterogeneity of cardiac surgery patients, the lack of any difference in outcome between the […]
Chaudhury et al. retrospectively analysed the outcomes of 769 consecutive adult patients with pulmonary embolism (PE) (as diagnosed by computed tomography PE protocol) for the 18 months prior to and after initiation […]
While the incidence of paediatric trauma requiring massive transfusion is lower than the incidence in adults, little is known regarding the optimal transfusion strategy in the paediatric population. Although optimal […]
The authors conducted a retrospective study to evaluate outcomes of severely injured trauma patients who received 4-factor prothrombin complex concentrate (4-PCC) + fresh frozen plasma (FFP) compared to FPP alone. […]
This is an excellent multicentre prospective randomised trial evaluating the efficacy of fibrinogen concentrate (FC) compared to cryoprecipitate to achieve haemostasis for infants post-cardiopulmonary bypass. The primary outcome was the […]
The authors noted that large academic centres are very likely to have a massive haemorrhage protocol (MHP) but smaller non-academic hospitals may not. Using a Modified Delphi Method, they convened […]
NATA: Network for the advancement of Patient Blood Management, Haemostasis and Thrombosis
MISSION: Providing a multidisciplinary forum for dialogue between haematologists, transfusion medicine specialists, anaesthesiologists, intensive care and emergency physicians, surgeons, perfusionists, nurses, biomedical scientists and ther heathcare professionals.
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