Incidence and risk factors for the development of anemia following gastric bypass surgery.
In order to evaluate the incidence and risk factors for the development of anemia after Roux-en-Y gastric bypass (RYGB), the authors performed a retrospective analysis... Read More
Platelet transfusion can be related to liver regeneration after living donor liver transplantation.
This interesting but retrospective study supports the hypothesis that platelet transfusion plays a significant and positive role in liver regeneration after living donor liver transplantation.... Read More
Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials.
The etiology of severe hemorrhage associated with trauma includes coagulopathy, hypothermia, acidosis, as well as platelet dysfunction, in addition to the direct effect of trauma... Read More
Survival advantage of using autologous blood transfusion during surgery for esophageal cancer.
This interesting article raises once again the issue of whether or not allogeneic transfusion can hasten the relapse of cancer and shorten overall survival. There... Read More
Effect of blood transfusion during radiotherapy on the immune function of patients with cancer of the uterine cervix: role of interleukin-10.
This article generates some good ideas and hypotheses about what might be causing, at the basic science level, the adverse treatment outcome effects of blood... Read More
Response predicting factors to recombinant human erythropoietin in cancer patients undergoing platinum-based chemotherapy.
This is a well done study of anemic cancer patients on cisplatin chemotherapy that documents nicely that the best predictor of an ultimate good response... Read More
Massive blood transfusion in the elective surgical setting.
Nice overview, but inconsistency between recommendations in the figures and in the text. – V. Kretschmer
Increased rate of infection associated with transfusion of old blood after severe injury.
This is a very important topic. All logical aspects would seem to suggest that stored cellular blood components have an immune suppressive effect. However, it... Read More
Transfusion in premature infants impairs production and/or release of red blood cells, white blood cells and platelets.
The author concludes that suppression of erythro-, leuko- and thrombopoiesis within 48 hours after transfusion decreases the amount of precursor cells in the peripheral blood.... Read More
The theory and practice of bloodless surgery.
A very thorough overview of all aspects of blood-sparing methods. – V. Kretschmer
Anemia and blood transfusion in critically ill patients.
The study of Vincent et al. gives excellent information concerning the frequency of blood transfusions in the intensive care unit (ICU) and the loss of... Read More
Efficacy of a low-dose intravenous iron sucrose regimen in peritoneal dialysis patients.
The authors evaluated a low dose iron substitution scheme for the effectiveness in patients with peritoneal dialysis: 50 mg iron sucrose every other week is... Read More
Epinephrine versus epinephrine plus fibrin glue injection in peptic ulcer bleeding: a prospective randomized trial.
A useful study (notwithstanding power) and review of current practices. – F. Regan and M. Contreras.
Clinical significance of RBC alloantibodies and autoantibodies in sickle cell patients who received transfusions.
The study shows that transfusion of blood matched for Rh and Kell systems would reduce alloimmunization to 27% and reduce delayed hemolytic transfusion reaction, but... Read More
Are lactated Ringer’s solution and normal saline solution equal with regard to coagulation?
This study compares the perioperative effects of a saline crystalloid and a more balanced and buffered electrolyte crystalloid on clotting. The differences thought to be... Read More