From the Literature


Published: Nov 2019

The use of a thromboelastometry-based algorithm reduces the need for blood product transfusion during orthotopic liver transplantation: A randomised controlled study.
Bonnet A, Gilquin N, Steer N, et al.
Eur J Anaesthesiol 2019;36:825-833.
Pub Med
NATA rating :


E. Adams


Orthotopic liver transplants have come a long way over the past several decades. While we have solved a myriad of problems leading to significantly improved outcomes, bleeding remains a problem.

This randomised controlled trial tested a thromboelastometry-based algorithm against standard practices. Intraoperative transfusion requirements were reduced in the thromboelastometry group, specifically FFP transfusions.

Orthotopic liver transplants are life-saving procedures associated with significant risk of bleeding and clotting. This study highlights a method where these risks may be further reduced.

– Eloa Adams (SABM reviewer)