From the Literature


Published: Nov 2019

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.
CRASH-3 trial collaborators
Lancet 2019;394:1713-1723.
Pub Med
NATA rating :


B. H. Hunt


Tranexamic acid administered within 3 hours of injury in patients with head trauma reduces death.

I know there has been criticism of the study design, but the results of this trial should change practice as it a low-cost intervention with no safety issues.

– Beverley J. Hunt