From the Literature


Published: Sep 2019

Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study.
Paciullo F, Bury L, Noris P, et al.
Haematologica 2019; Sep 26 [Epub ahead of print].
Pub Med
NATA rating :


B. H. Hunt


This is a retrospective study of patients with inherited platelet disorders undergoing surgical procedures. No protocol was followed, and mechanical and pharmacological thromboprophylaxis was used at clinical discretion.

There were patients with clinical VTE. There were patients who bled. Disappointingly, only a minority got perioperative tranexamic acid. It emphasises the need for RCTs in this area.

– Beverley J. Hunt