From the Literature


Published: Oct 2019

Iron deficiency is associated with higher mortality in patients undergoing cardiac surgery: a prospective study.
Rössler J, Schoenrath F, Seifert B, et al.
Br J Anaesth 2019; Oct 23 [Epub ahead of print].
Pub Med
NATA rating :


E. Adams


This very interesting prospective study looked at four patient cohorts undergoing cardiac surgery: patients without aneemia with and without iron deficiency and patient with anaemia with and without iron deficiency. The primary outcomes were 90-day mortality, serious adverse events, major cardiac and cerebrovascular events, transfusions, and prolonged hospital stay.

The study found that 90-day mortality was increased in iron-deficient patients with and without anaemia. Patient with iron deficiency also had more serious adverse events and prolonged hospital stays.

This study suggests that patients with iron deficiency, even in the absence of anaemia, should be treated prior to undergoing cardiac surgery.

– Eloa Adams (SABM reviewer)